Lung Cancer

Risk Factors

The American Cancer Society defines a risk factor as anything that increases a person's chance of getting a disease such as cancer. According to ACS, different cancers have different risk factors. For example, unprotected exposure to strong sunlight is a risk factor for skin cancer, and smoking is a risk factor for lung cancer. According to the American Cancer Society, the following are risk factors for lung cancer:

Tobacco smoking: Tobacco smoking is thought to be responsible for 8 out of 10 cases of lung cancer. The longer a person has been smoking and the more packs per day smoked, the greater the risk. If a person stops smoking before lung cancer develops, the lung tissue slowly returns to normal. Stopping smoking at any age lowers the risk of lung cancer. Cigar and pipe smoking are almost as likely to cause lung cancer as cigarette smoking. There is no evidence that smoking low tar cigarettes reduces the risk of lung cancer.

Nonsmokers who breathe the smoke of others also increase their risk of lung cancer. Non-smoking spouses of smokers, for example, have a 30% greater risk of developing lung cancer than do spouses of nonsmokers. Workers exposed to tobacco smoke in the workplace are also more likely to get lung cancer.

Asbestos: Asbestos is another risk factor for lung cancer. People who work with asbestos have a higher risk of getting lung cancer, and if they smoke as well, the risk is greatly increased. Although asbestos was used for many years, the government has now nearly stopped its use in the workplace and in home products. The type of lung cancer linked to asbestos, mesothelioma, often starts in the pleura. To learn more about this type of cancer, please see our Cancer Reference Information section on Mesothelioma.

Radon: Radon is a radioactive gas produced by the natural breakdown of uranium. Radon can't be seen, tasted, or smelled. Radon can become concentrated indoors and create a possible risk for cancer. The EPA (Environmental Protection Agency) can provide the names of reliable companies that test for radon gas.

Cancer-causing agents in the workplace include substances such as uranium, arsenic, vinyl chloride, nickel chromates, coal products, mustard gas, chloromethyl ethers, gasoline, and diesel exhaust. People who work with or around these substances should be very careful to avoid exposure.

Marijuana: Marijuana cigarettes have more tar than regular cigarettes. Many of the cancer-causing substances in tobacco are also found in marijuana. Some medical reports suggest that marijuana could cause cancers of the mouth and throat. But because marijuana is an illegal substance, it is not easy to gather information about its effects.

Other diseases: Tuberculosis (TB) and some types of pneumonia often leave scars on the lung. This scarring can increase the risk of developing lung cancer.

Minerals: Talc may increase the risk of lung cancer in those who mine or work with it. People with diseases caused by breathing certain minerals also have an increased risk.

Personal and family history: If you have had lung cancer, you are at a higher risk of developing another lung cancer. Brothers, sisters, and children of people who have had lung cancer may have a slightly higher risk themselves.

Diet: Some reports suggest that a diet low in fruits and vegetables might increase the risk of lung cancer in people who are exposed to tobacco smoke. It is possible that apples, onions, and some other fruits and vegetables could contain a substance that offers some protection against lung cancer.

Gender: Several studies have shown that the lung cells of women are more likely to develop cancer when exposed to tobacco smoke.

During the past few years, scientists have made great progress in understanding how risk factors produce certain changes in the DNA of lung cells, causing the cells to become cancerous. DNA is the genetic material that carries the instructions for nearly everything our cells do.

Current research in this field is aimed at developing tests that can detect lung cancers at an early stage by recognizing DNA changes. Other researchers are working on ways to repair or replace these faulty genes in order to stop the growth and spread of cancer cells.

Support & Information

Alliance for Lung Cancer Advocacy, Support, and Education
ALCASE is a national not-for-profit organization dedicated exclusively to helping people with lung cancer, and people who are at risk for the disease to improve the quality of their lives through advocacy, support, and education.

American Lung Association
Information about lung cancer, the treatments, signs and symptoms, causes, how to prevent lung cancer, new data, and research.

The Roy Castle Lung Cancer Foundation
Charity dedicated to defeating lung cancer. This site includes survival stories, current news and updates, research programs focusing on detecting lung cancer in its early stages, support groups, and other information.

New York Early Lung Cancer Action Program
Information on an action program focused on clients who are 60 years of age or older, have smoked 1 pack of cigarettes a day for 10 years, have no personal history of cancer, and who are in generally good health.

Women and Lung Cancer
A site dedicated to informing women about lung cancer. Women can learn about early detection signs and symptoms. Also, includes treatment options for women already diagnosed with lung cancer.